OSU SCIENTISTS DISCOVER REGULATING MECHANISM IN CELLS
OSU SCIENTISTS DISCOVER REGULATING MECHANISM IN CELLS -- Researchers at Ohio State have discovered a mechanism used by cells -- and manipulated by retroviruses -- to control production of certain essential proteins, including some involved in cancer. The mechanism uses an enzyme called RNA helicase A (RHA), which is made by the cell. The study, by researchers at the OSU Comprehensive Cancer Center - The James (OSUCCC - James) and the OSU College of Veterinary Medicine, appears in the May issue of the journal Nature Structural and Molecular Biology. "Our findings provide important insights into how cells regulate certain growth-proteins, many of which play an important role in cancer, and how viruses use cell mechanisms to establish an infection," says principal investigator Kathleen Boris-Lawrie, PhD, a researcher with the OSUCCC's Viral Oncogenesis Program.
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