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June 14, 2007
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COLUMBUS, Ohio – If one considers the body a battleground between infectious bugs and the human immune system, then a highly specialized group of medical researchers at Ohio State University could be ...
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March 07, 2007
COLUMBUS, Ohio—Dr. John Gunn (43065) of the Ohio State University Medical Center has received a five-year, $1.4 million grant for a study on the relationship between salmonella infections, gallstones ...
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December 17, 2006
New research identifying a key enzyme’s role in sepsis - a blood infection that can lead to organ failure, shock and death - may help determine the course of critically ill patients’ response to the life-threatening infection and aid in development of drugs to reduce its damage. Researchers at the OSU Medical Center found that the enzyme caspase-1 contributes to the process by which patients become infected with sepsis. More than 500,000 people develop sepsis annually and 175,000 of them die in the United States. The research was published in the American Journal of Respiratory Critical Care Medicine.
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June 20, 2006
A protein made by a cancer-causing virus using an unusual gene enables that virus to infect immune cells and persist in the host, new research shows.
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May 30, 2006
A new study at OSU reveals how the production of a potent immune regulator called interferon gamma (IFNg) is controlled in natural killer (NK) cells -- immune cells that typically defend the body against cancer and infections. IFNg, produced by NK cells and other cell types, plays a critical role in killing pathogen-infected cells and in defending against tumor cells.
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May 19, 2006
Researchers at Ohio State have discovered a mechanism used by cells -- and manipulated by retroviruses -- to control production of certain essential proteins, including some involved in cancer.
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May 15, 2006
-- Kurt B. Stevenson of the OSU Medical Center is among the recipients of a Centers for Disease Control and Prevention $10 million grant to study approaches to reducing infections in health care settings.
Shared between five institutions, the grant will focus on improving surveillance for health care-associated infections using electronic health information.
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April 24, 2006
New research at OSU shows that a protein made by a cancer virus causes infected immune cells to cling to other immune cells, enabling the virus to spread. The virus, known as the human T lymphotropic virus type 1 (HTLV-1), is transmitted mainly when infected cells called T lymphocytes, or T cells, touch uninfected T cells.
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